Parameters

Aliskiren (n = 11)

Losartan (n = 11)

p value

Age (years)

41 (33 - 52)

44 (36 - 61)

0.224

Male

3 (13.6%)

8 (36.4%)

0.086

Female

8 (36.4%)

3 (13.6%)

Weight (kg)

66.4 (61.0 - 76.0)

74.0 (56.0 - 83.0)

0.847

Height (cm)

164.0 (160.0 - 170.0)

170.0 (155.0 - 175.0)

0.973

Body mass index (kg/m2)

22.24 (21.40 - 25.85)

25.43 (23.82 - 28.14)

0.203

Blood pressure in mmHg

Systolic BP

133 (128 - 140)

140 (130 - 158)

0.356

Diastolic BP

80 (67 - 90)

80 (70 - 88)

0.716

Primary Glomerulonephritis

Ig AN

9 (40.9%)

7 (31.8%)

1.0

FSGS

2 (9.1%)

3 (13.6%)

Membranous

0 (0%)

1 (4.5%)

Age at diagnosis (years)

32 (28 - 40)

38 (28 - 55)

0.189

Disease duration (years)

5 (2 - 7)

6 (3 - 9)

0.355

Baseline Co-Morbidities

Hypertension

4 (40%)

7 (87.5%)

0.066

Dyslipidaemia

6 (60%)

5 (62.5%)

1.000

Smoking

1 (10%)

0 (0%)

1.000