Parameters | Aliskiren (n = 11) | Losartan (n = 11) | p value |
Age (years) | 41 (33 - 52) | 44 (36 - 61) | 0.224 |
Male | 3 (13.6%) | 8 (36.4%) | 0.086 |
Female | 8 (36.4%) | 3 (13.6%) | |
Weight (kg) | 66.4 (61.0 - 76.0) | 74.0 (56.0 - 83.0) | 0.847 |
Height (cm) | 164.0 (160.0 - 170.0) | 170.0 (155.0 - 175.0) | 0.973 |
Body mass index (kg/m2) | 22.24 (21.40 - 25.85) | 25.43 (23.82 - 28.14) | 0.203 |
Blood pressure in mmHg | |||
Systolic BP | 133 (128 - 140) | 140 (130 - 158) | 0.356 |
Diastolic BP | 80 (67 - 90) | 80 (70 - 88) | 0.716 |
Primary Glomerulonephritis | |||
Ig AN | 9 (40.9%) | 7 (31.8%) | 1.0 |
FSGS | 2 (9.1%) | 3 (13.6%) | |
Membranous | 0 (0%) | 1 (4.5%) | |
Age at diagnosis (years) | 32 (28 - 40) | 38 (28 - 55) | 0.189 |
Disease duration (years) | 5 (2 - 7) | 6 (3 - 9) | 0.355 |
Baseline Co-Morbidities | |||
Hypertension | 4 (40%) | 7 (87.5%) | 0.066 |
Dyslipidaemia | 6 (60%) | 5 (62.5%) | 1.000 |
Smoking | 1 (10%) | 0 (0%) | 1.000 |